In our Annual Energy Outlook 2025 (AEO2025), we project regional differences in natural gas markets will encourage increased natural gas flows from the mid-Atlantic to the southern Gulf Coast in the coming decades. Across the cases we explored, we project production from the Appalachian Basin in the mid-Atlantic and Ohio region will increasingly meet growing demand on the Gulf Coast in the South Central region, driven largely by increasing liquefied natural gas (LNG) exports. The economics of increased production in the Appalachian Basin are more favorable by 2030, and our model shows natural gas transiting through the Eastern Midwest region on the way to the Gulf Coast.